In a major advance for rare disease research, a patient who endured unexplained immunodeficiency, developmental disorders, and lymphoma for 16 years has finally received a genetic diagnosis. A collaborative team from Seoul National University Hospital and Chung-Ang University has, for the first time, established that mutations in the BRF2 gene can directly cause such conditions, while also uncovering the underlying disease mechanisms—a world first.The study was jointly led by Professor Jong-Hee Chae's team at Seoul National University Hospital and Professor Keun Pil Kim's team at Chung-Ang Un
For the first time, researchers have identified a critical role for the protein ATE1 in promoting tumor growth in breast cancer, offering new insights into potential biomarkers and targeted therapies. The findings, published in the September 2 online edition of Cell Communication and Signaling, mark a significant step forward in understanding the complex behavior of this enzyme in cancer.ATE1, an enzyme that modifies cellular proteins through a process called arginylation, has long puzzled scientists due to its contradictory roles across different cancers. Previous studies showed that ATE1 sup
A new study from Jaseng Hospital of Korean Medicine in South Korea found that herbal medicine may significantly reduce both the incidence and severity of radiation-induced esophagitis (RIE), a common complication of radiation therapy for thoracic cancers such as lung, esophageal, and breast cancer. Published in the international journal Integrative Cancer Therapies (Impact Factor: 3.077), the research highlights the potential of traditional Korean herbal treatments to complement conventional care, offering hope for improved quality of life among cancer patients undergoing radiation.Radiation-i
A new study reveals that survival rates for patients with advanced cancer can more than double depending on the quality of palliative care they receive, while depressive symptoms decrease significantly. This groundbreaking research is the first to demonstrate that it is not merely the availability of palliative care, but its quality, that profoundly influences patients' lives and outcomes.Patients with progressive cancer face not only treatment challenges but also pain, depression, anxiety, and other issues. While early palliative care is intended to provide support, efforts until now have la
