- 향후 5년 ‘제2형 당뇨병’ 발병 예측
- 개인 맞춤형 조기 진단 및 예방책 도출 기대
The project was led by Dr. Nan-Hee Kim of the Department of Endocrinology and Metabolism, with Drs. So-Young Park, Min-Hee Kim, and Jae-Young Kim. The system forecasts diabetes risk using clinical indicators and genetic markers tailored to specific ethnic populations.
Type 2 diabetes, which accounts for around 90% of all diabetes cases, is caused by insulin resistance influenced by genetic predisposition and environmental factors such as aging, obesity, medication use, and chronic stress. Given the challenges of treatment and the severity of complications, prevention remains critical. The researchers believe the system could enable early, individualized interventions by integrating both environmental and genetic risk data into clinical decision-making.
The system includes five components: (1) a database module to store and manage clinical and genetic data; (2) a processing unit that analyzes the frequency of genetic variants using ethnicity-specific datasets; (3) a prediction module that estimates the five-year risk of developing diabetes; (4) an analysis unit that identifies contributing risk factors; and (5) a reporting module that delivers personalized diagnostic and preventive recommendations.
“This system delivers precise risk assessment by combining personal, genetic, and lifestyle factors,” Dr. Kim said. “It allows us to pinpoint high-risk periods for diabetes onset, enabling timely preventive measures.”
The research team operates out of Korea University Anam Hospital and its Biomedical Research Center. Drs. Kim and Park are affiliated with the Department of Endocrinology and Metabolism, while Drs. Min Hee Kim and Jae Young Kim are with the Biomedical Research Center.
Lim Hye Jung, HEALTH IN NEWS TEAM
press@hinews.co.kr
